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Welcome to RX EU Medication Online. We are a pharmaceutical store based in Europe and we focus more on pain medications. We have a wide range of products from different manufacturers, including some generic drugs. All our medicines are available at very affordable prices. Our online pharmacy is one of the best places where you can buy your medication with ease and convenience. You don’t need to visit any local pharmacies or shops for buying these drugs. Just place an order and get it delivered right at your doorstep.
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RX EU MEDICATIONS
Welcome to RX EU Medication Online. We are a pharmaceutical store based in Europe and we focus more on pain medications. We have put together quality pain drugs that meets customer quality. We have been in business for long and our goal has always been to provide high quality medications at affordable prices. Our customers come from all over the world, so you can be sure that they will receive their orders in good time with no delays or problems.
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Benzodiazepines are a class of psychoactive drugs that have been used for many years to treat anxiety and insomnia. Benzodiazepines work by increasing the activity of certain neurotransmitters in the brain, including gamma-aminobutyric acid . The most commonly prescribed benzodiazepine is diazepam, which was first introduced into clinical practice in 1955. It has since become one of the best selling prescription medicines worldwide. Other benzodiazepines include alprazolam , clonazepam , lorazepam , midazolam and temazepam .
The history of benzodiazepines began with the discovery of chlordiazepoxide in 1953. Chlordiazepoxide was found to be an effective anti-anxiety agent and was marketed as Librium. In 1957, diazepam was discovered. This drug was also effective at treating anxiety but had fewer side effects than Librium. Diazepam became the world’s best selling medicine in 1963. By 1970, it had overtaken Librium in sales.
Society and culture
The use of benzodiazepines is widespread and their popularity continues to grow. According to the World Health Organization, they were among the top ten most frequently prescribed medications in 2004. Worldwide consumption of these drugs increased from 1.2 million tons in 1990 to 2.4 million tons in 2005. They are widely available over the counter in many countries.
Benzodiazepines possess psycholeptic, sedative, hypnotic, anxiolytic, anticonvulsant, muscle relaxant, and amnesic actions, which are useful in a variety of indications such as alcohol dependence, seizures, anxiety disorders, panic, agitation, and insomnia. They are also used in the treatment of alcohol withdrawal syndrome.
Because of their effectiveness, tolerability, and rapid onset of anxiolytic action, benzodiazepines are frequently used for the treatment of anxiety associated with panic disorder. However, there is disagreement among expert bodies regarding the long-term use of benzodiazepines for panic disorder. The views range from those holding benzodiazepines are not effective long-term and should be reserved for treatment-resistant cases to those holding they are as effective in the long term as selective serotonin reuptake inhibitors (SSRIs).
Generalized anxiety disorder
Benzodiazepines have robust efficacy in the short-term management of generalized anxiety disorder (GAD), but were not shown effective in producing long-term improvement overall. According to National Institute for Health and Clinical Excellence (NICE), benzodiazepines can be used in the immediate management of GAD, if necessary. However, they should not usually be given for longer than 2–4 weeks. The only medications NICE recommends for the longer term management of GAD are antidepressants
Benzodiazepines are sometimes used in the treatment of acute anxiety, as they bring about rapid and marked relief of symptoms in most individuals; however, they are not recommended beyond 2–4 weeks of use due to risks of tolerance and dependence and a lack of long-term effectiveness. As for insomnia, they may also be used on an irregular/”as-needed” basis, such as in cases where said anxiety is at its worst. Compared to other pharmacological treatments, benzodiazepines are twice as likely to lead to a relapse of the underlying condition upon discontinuation.
Benzodiazepines can be useful for short-term treatment of insomnia. Their use beyond 2 to 4 weeks is not recommended due to the risk of dependence. The Committee on Safety of Medicines report recommended that where long-term use of benzodiazepines for insomnia is indicated then treatment should be intermittent wherever possible. It is preferred that benzodiazepines be taken intermittently and at the lowest effective dose
Prolonged convulsive epileptic seizures are a medical emergency that can usually be dealt with effectively by administering fast-acting benzodiazepines, which are potent anticonvulsants. In a hospital environment, intravenous clonazepam, lorazepam, and diazepam are first-line choices. In the community, intravenous administration is not practical and so rectal diazepam or buccal midazolam are used, with a preference for midazolam as its administration is easier and more socially acceptable
Chlordiazepoxide is the most commonly used benzodiazepine for alcohol detoxification, but diazepam may be used as an alternative. Both are used in the detoxification of individuals who are motivated to stop drinking, and are prescribed for a short period of time to reduce the risks of developing tolerance and dependence to the benzodiazepine medication itself